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General Electric Senior Scientist (Nonclinical/Biologist) in Chalfont St Giles, United Kingdom

Job Description Summary

This role is for a Senior Scientist and will support the development of diagnostic imaging agents that will make a real impact on the lives of people suffering from cardiovascular and neurological diseases as well as cancer.

Job Description

For this position, reporting to the Head of Non-Clinical Sciences, you will bring your scientific experience, biology expertise and ability to work in a team cross functionally to lead the non-clinical aspects of developing imaging diagnostic agents for the diagnosis, differentiation and therapy monitoring of diseases. You will have good knowledge of toxicology, safety or pharmacology/biology in one of the key areas of cardiology, neurology or oncology and this role is particularly suited if you have previous relevant experience in non-clinical drug development or regulatory submissions.

The position is non-laboratory based and will appeal to you if you enjoy working on multiple projects across areas beyond your experience, where your ability to rapidly assimilate information and build relationships with established internal teams and external collaborators is viewed as essential. You will be a critical part of a small team working on a broad portfolio of molecular, contrast or ultrasound imaging products in all stages of development, regulatory submissions and the life cycle management of approved products.

Essential Responsibilities

  • Use your experience of in vitro and in vivo biology with your ability to gain knowledge to build understanding into disease areas, biological mechanisms and diagnostic targets. Design strategies and studies addressing pharmacology/efficacy, safety or other relevant non-clinical aspects to support drug development.

  • Plan and manage effectively non-clinical study programmes, defining milestones and timelines, understanding the risks and opportunities and use your relationship and communication skills to align with other functions (especially chemistry, radiochemistry, clinical and regulatory affairs) to ensure they are fit-for-purpose.

  • Deliver studies within the R&D’s externalisation model by working closely with external research organisations, supporting academic and CRO collaborations and developing an external network

  • Work within a multidisciplinary team to perform due diligence assessments of in-licencing opportunities, confidentially evaluating the non-clinical data and likely success of the product

  • Write and review high quality documents such as those required for regulatory submissions, safety risk assessments and publications. Be a subject matter expert for your projects to support other functions and address enquires from external parties such as Health Authorities

  • Represent the Company at external meetings and co-authoring scientific papers for publication in refereed journals


  • A PhD or equivalent in Biology, Pharmacology, Life Sciences or related field with a minimum 5 years post-doctoral or industry experience

  • Experience and understanding in the field of cardiology, neurology or oncology, with a focus on the areas relevant to therapeutic or diagnostic drug development

  • An understanding of imaging (PET, SPECT, CT, MR or ultrasound) is desired, but not essential

  • Previous experience with regulatory submissions, GLP safety/toxicology studies, safety risk assessments is preferred, but not critical

  • A high degree of initiative and the ability to work systematically and independently is expected

  • Proven ability to write high quality documentation in English

  • Good communication skills

Inclusion and Diversity

GE Healthcare is an Equal Opportunity Employer where inclusion matters. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status or other characteristics protected by law.

Our total rewards are designed to unlock your ambition by giving you the boost and flexibility you need to turn your ideas into world-changing realities. Our salary and benefits are everything you’d expect from an organization with global strength and scale, and you’ll be surrounded by career opportunities in a culture that fosters care, collaboration and support.

About us

GE Healthcare is a leading global medical technology and digital solutions innovator. Our mission is to improve lives in the moments that matter. Unlock your ambition, turn ideas into world-changing realities, and join an organization where every voice makes a difference, and every difference builds a healthier world.

As a federal government contractor, GE requires U.S. employees to be fully vaccinated against COVID-19 unless you receive an approved medical or religious accommodation. Proof of vaccination will be required .


Additional Information

Relocation Assistance Provided: No